局部背痛的特征和负担与背痛与慢性重叠疼痛状况的背痛
Abdullah Sulieman Terkawi1, Rita A Popat2, Sean Mackey1
1Division of Pain Medicine, Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University, Palo Alto, California, USA.
概括
慢性腰部疼痛 (cLBP) 和慢性重叠疼痛 (COPCs) 患者体验到更糟糕的身体,心理和社会功能. 在cLBP患者中识别COPC可以改善风险分层和个性化治疗策略.
科学领域:
- 疼痛医学 医学 疼痛医学
- 类风湿病学 类风湿病学
- 康复医学 康复医学 康复医学
背景情况:
- 慢性腰部疼痛 (cLBP) 是全球导致残疾的主要原因.
- 慢性重叠疼痛条件 (COPCs) 代表了广泛疼痛研究的日益增长的领域.
- COPCs对cLBP患者的影响仍未得到充分研究.
研究的目的:
- 描述和比较单独cLBP患者与cLBP患者和相关的COPC患者的身体,心理和社会功能.
- 调查局部cLBP和广泛的疼痛条件之间的健康结果的差异.
- 为患有COPC的cLBP患者提供风险分层和个性化管理的信息.
主要方法:
- 这是一项使用斯坦福大学CHOIR注册表进行的横截面研究.
- 将局部cLBP (L组) 与cLBP和COPC (W组) 的患者进行比较.
- 使用了人口统计,PROMIS和传统调查数据;使用了描述性统计和通用线性回归模型.
主要成果:
- 在8783名cLBP患者中,5.5%的患者有局部疼痛 (L组);其余的患者有普遍疼痛 (W组).
- 组W患者更有可能是女性,年轻,疼痛持续时间更长,在疲劳,睡眠,疼痛行为,身体功能,疼痛干扰和焦虑方面显著恶化PROMIS结果.
- 经过调整后的分析证实了恶化结果与更广泛的疼痛,表明超过平均疼痛得分的显著临床影响.
结论:
- 在患有cLBP的患者中,COPC是常见的并发症.
- COPCs的存在显著加剧了cLBP患者的身体,心理,社会和整体健康结果.
- 在cLBP患者中识别COPC对于有效的风险分层和个性化治疗计划至关重要.
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