儿童IgE介导过敏和复杂尾炎之间的关系
Zhiyi Zhang1, Li Wang2, Chuanping Xie1
1Department of General Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, No. 56 Nanlishi Road, Xicheng District, Beijing, 100045, China.
Pediatric surgery international
|July 1, 2023
概括
患有IgE介导过敏的儿童患复杂尾炎 (CA) 的风险降低. 在这项儿科研究中,过敏对尾切除术后的预后没有影响.
科学领域:
- 儿科手术 儿科手术
- 过敏 免疫学 免疫学
- 胃肠道疾病 胃肠道疾病
背景情况:
- 复杂性尾炎 (CA) 在儿科患者中存在重大风险.
- 对于IgE介导过敏对尾炎结局的作用尚不清楚.
研究的目的:
- 调查IgE介导过敏和复杂尾炎 (CA) 的发展之间的关联.
- 评估IgE介导过敏对接受尾切除手术的儿科患者预后的影响.
主要方法:
- 对1156名患有急性尾炎 (AA) 的儿科患者的回顾性分析.
- 患者根据IgE介导过敏的存在或不存在来分类.
- 使用后勤回归分析,对临床和实验室变量进行调整,以评估过敏和CA之间的关联.
主要成果:
- 16.0%的患者患有IgE介导的过敏.
- 患有IgE介导过敏的儿童患CA的风险显著降低 (调整后OR=0.582,P=0.023).
- 两组之间在手术时间,住院时间,再入院率或粘合性肠道阻塞方面没有发现显著差异.
结论:
- 通过IgE介导的过敏与儿童复杂尾炎风险降低有关.
- 过敏状况似乎不会影响这个儿科队列中尾切除术后的预后.
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