利用希夫的测试和形试验,有效地评估基于酒精的手部消毒剂的质量
Chirapha Prakobdi1, Duangjai Nacapricha1, Thanthapatra Bunchuay2
1Flow Innovation-Research for Science and Technology Laboratories (Firstlabs), Thailand; Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
概括
这项研究提出了一项新的酒精手洗手剂质量评估,以检测有毒甲醇造和量化乙醇. 开发的方法确保了消毒剂的安全性和对病毒的有效性,这在COVID-19大流行期间至关重要.
科学领域:
- 分析化学 分析化学
- 公共卫生 公共卫生
背景情况:
- 在COVID-19大流行期间,基于酒精的手部消毒剂对消毒至关重要.
- 有关甲醇改和在消毒剂中精确量化乙醇存在担忧.
研究的目的:
- 开发和介绍基于酒精的手部消毒剂的综合质量评估.
- 为了检测甲醇改并准确量化乙醇度.
主要方法:
- 在氧化成甲后使用希夫试剂检测甲醇,在591nm检测.
- 通过具有度检测的形反应量化乙醇.
- 根据综合测试结果,制定一个规则图表,其中包含四个安全区.
主要成果:
- 建立了一种用于检测手洗手剂中甲醇改的新方法.
- 实现了合法酒精 (乙醇或异醇) 的量化.
- 开发的调节图表显示与气色谱-火焰电离探测器结果一致.
结论:
- 该研究提供了首次对基于酒精的手洗手剂的完整质量评估.
- 这些新方法确保了手消毒剂的安全性和有效性,解决了关键的公共卫生问题.
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