代表性漂移作为一个进入神经和行为可塑性的窗口
Charles Micou1, Timothy O'Leary2
1Department of Engineering, University of Cambridge, United Kingdom.
Current opinion in neurobiology
|July 1, 2023
概括
神经表现随着时间的推移不断变化,即使没有行为转变. 这项研究表明,一种学习规则驱动这种神经漂移,为大脑可塑性提供了洞察力.
科学领域:
- 神经科学是一个神经科学.
- 计算神经科学是一种神经科学.
- 系统神经科学 系统神经科学
背景情况:
- 大规模的神经记录显示神经表征在几天/几周内不断演变.
- 这种神经漂移发生在任务,感知或行动中没有明显的行为变化.
研究的目的:
- 为了研究这样一个假设,即学习规则的持续应用驱动神经漂移.
- 探索神经漂移如何揭示生物可塑性的系统级性质.
主要方法:
- 在长时间内对大规模神经记录进行分析.
- 观察到的神经漂移与使用代学习的神经网络模型预测的比较.
主要成果:
- 神经漂移是一种可测量的现象,与正在进行的学习过程有关.
- 具有代重量优化的神经网络模型预测了类似的漂移模式.
结论:
- 在细胞和人口层面不断应用学习规则可能会导致神经漂移.
- 神经漂移是理解生物可塑性机制的精度和学习速率的有价值信号.
相关概念视频
Neuroplasticity
588
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
588
Plasticity
2.2K
Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
2.2K
Instinctive Drift
254
Instinctive drift refers to the tendency of animals to revert to their innate behaviors despite repeated reinforcement. Breland and Breland demonstrated this concept in an experiment with a raccoon. The raccoon was trained to pick up two coins and place them in a container in exchange for food. Initially, the raccoon learned to associate the coins with food, making them a conditioned stimulus or a substitute for food. However, over time, the raccoon became less willing to put the coins into the...
254
Revisionist Views of Adolescent and Adult Cognition
64
A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are...
64
Long-term Potentiation
2.8K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
Hebbian LTP
LTP can occur when...
2.8K
Neural Regulation
39.6K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.6K


