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人类细胞染色体P450 3A7与其原生基质脱水三硫酸三硫酸盐的四个副本结合

Jinghan Liu1, Sylvie E Kandel2, Jed N Lampe2

  • 1Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA.

The Journal of biological chemistry
|July 1, 2023
PubMed
概括

人类胎儿细胞染色体P450 3A7 (CYP3A7) 结合其基质脱氨3-硫酸盐 (DHEA-S) 的四个副本,揭示了复杂的相互作用. 这种结构洞察力有助于对CYP3A7的理解.

关键词:
在 CYP3A7A7 中.在DHEA-S中使用.在X射线晶体学.细胞染色体P450的使用.脱水安德罗斯特硫酸盐脱水安德罗斯特硫酸盐酶动力学 酶动力学类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型:

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