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与糖尿病儿科患者中脱脂症的发展相关的因素:基于单中心的单中心研究
Fahd Alshammri1, Hannah Geddie1, Noor Sawalha1
1Department of Pediatrics, McMaster Children's Hospital, McMaster University, Hamilton, Ontario, Canada.
儿童糖尿病患者经常患有失脂血症,这是一种关键的心脏病风险因素. 许多患有糖尿病的儿童被查失脂症,但并不总是按照指导方针进行,近一半患有这种疾病.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 心血管风险管理心血管风险管理
背景情况:
- 儿科糖尿病患病率的增加需要积极管理相关的心血管疾病风险因素.
- 失脂症是糖尿病儿童心血管疾病的重要,可修改的危险因素.
研究的目的:
- 评估儿童糖尿病计划中遵守加拿大糖尿病2018年脂质查指南.
- 为了确定患有糖尿病的年轻人中脱脂症的患病率.
- 在这个人群中识别与失脂血症相关的危险因素.
主要方法:
- 在麦克马斯特儿童医院对305名患者 (1型和2型糖尿病,≥12岁) 的回顾性图表审查.
- 收集的数据包括人口统计,糖尿病史,BMI,A1C和脂质资料.
- 统计分析涉及描述性统计和物流回归.
主要成果:
- 61%的患者符合脂质查指南标准;29%的患者在推窗口之外进行了查.
- 45%的查患者表现出脱脂症,主要是高甘油三血症 (35%).
- 患有2型糖尿病,肥胖,年龄较大,糖尿病持续时间较长,A1C较高以及使用毛细血管血糖监测的患者的失脂症风险更高.
结论:
- 虽然查遵守率很高,但时间往往不够理想.
- 脱脂症在儿科糖尿病患者中非常普遍,即使在没有肥胖的人群中也是如此.
- 针对性的干预措施对于管理患有糖尿病的年轻人的失脂症至关重要.
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