肌神经系统的结构功能特性:异质性的证据和对肌肉功能的影响
Benjamin B Wheatley1, Olivia L Dyer2, Emily E Tully1
1Department of Mechanical Engineering, Bucknell University, Lewisburg, PA.
Acta biomaterialia
|July 1, 2023
概括
肌神经,一种连接组织,在肌肉和肌区域之间表现出不同的微观结构和性. 考虑到这种异质性对于准确的肌肉骨模型至关重要.
科学领域:
- 生物力学 生物力学
- 连接组织研究 连接组织研究
- 肌肉骨系统分析
背景情况:
- 肌肉神经系统在肌肉骨系统内的力传递中起着至关重要的作用.
- 了解肌神经系统的结构-功能关系是有限的,影响肌单元机制.
- 现有的模型往往忽略了aponeurosis异质性.
研究的目的:
- 为了研究猪三手臂神经神经神经神经系统的异质材料特性.
- 为了与其机械行为相关联aponeurosis微观结构.
- 评估神经异质性对计算模型的影响.
主要方法:
- 材料测试猪三腕肌神经.
- 扫描电子显微镜用于分析组织微观结构.
- 有限元建模模拟肌单位力学.
主要成果:
- 脊髓炎在插入区域与过渡区域相比,在插入区域表现出更大的原蛋白波动.
- 与过渡区域相比,插入区域的应激应变反应较少硬.
- 脊髓瘤弹性模块的变化显著改变了模型的刚性和应变.
结论:
- 脊髓神经异质性可能源于组织微观结构的变化 (原波动性).
- 脊髓神经瘤的位置依赖性物质性质影响其机械功能.
- 准确的肌肉骨模型需要结合aponeurosis异质性,挑战统一的假设.
相关概念视频
Gross Anatomy of Skeletal Muscles
12.5K
The connective tissues play a significant role in arranging the muscle fibers into a hierarchical structure that forms a complete muscle. Consider a muscle like the bicep brachii, commonly called the bicep. This muscle comprises thousands of muscle fibers enclosed by a protective layer of connective tissue called the endomysium. The endomysium is primarily composed of reticular fibers, a type of thin collagen fiber. It allows the exchange of nutrients and waste products at the fiber level,...
12.5K
Skeletal Muscle Anatomy
89.2K
Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.
89.2K
Overview of Skeletal Muscle
11.8K
Skeletal muscles are composed of a bundle of muscle fibers and are attached to bones through tendons. Each skeletal muscle fiber is a single muscle cell. The sarcolemma, the plasma membrane of a skeletal muscle cell, consists of a lipid bilayer and glycocalyx that supports muscle fibers. The sarcolemma extends into the muscle cells to form tubular structures called transverse or T-tubules. Each side of the T-tubules consists of a membrane-bound structure called the sarcoplasmic reticulum,...
11.8K
Overview of Muscle Tissues
12.3K
The human body has three types of muscle tissue: skeletal, smooth, and cardiac. Each class has unique properties that enable them to perform specific functions. However, all muscle tissues share certain properties, including elasticity, contractility, and excitability.
Elasticity
Elasticity is the ability of muscles to stretch and return to their original shape. This property is partly due to elastic fibers — macromolecules that run through the muscles. These fibers are firm and...
Elasticity
Elasticity is the ability of muscles to stretch and return to their original shape. This property is partly due to elastic fibers — macromolecules that run through the muscles. These fibers are firm and...
12.3K
The Neuromuscular Junction
9.9K
The nervous system consists of complex motor neuron circuits, including upper motor neurons originating from the cerebral cortex and lower motor neurons starting in the spinal cord, coordinating both voluntary and involuntary movements. Among these, somatic motor neurons activate skeletal muscles and are classified into alpha, beta, and gamma types. Alpha neurons are vital for voluntary movement coordination, while gamma neurons adjust muscle spindle sensitivity, and the function of beta...
9.9K
Structure and Organization of Smooth Muscles
5.9K
Smooth muscle tissue is a type of muscle tissue that can be found lining various vital organs in the human body, including the lungs, blood vessels, digestive tract, and respiratory tract. This type of tissue is responsible for regulating the movements of these organs, playing crucial roles in the functioning of various systems, including the vascular, digestive, respiratory, and urinary systems.
Structure of smooth muscle cell
Smooth muscle cells are spindle-shaped with tapering ends and a...
Structure of smooth muscle cell
Smooth muscle cells are spindle-shaped with tapering ends and a...
5.9K


