相关实验视频
Updated: Jul 24, 2025

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Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
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由Alternaria alternata感染引起的孔在一个免疫能力强的青少年中
Junjun Chen1, Hui Yao1, Xiaoling Yuan2
1Department of Oral Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai, China.
概括
一种罕见的由Alternaria alternata引起的真菌感染导致一个健康的青少年口腔穿孔. 这一案例凸显了在无法解释的口腔病变中需要考虑A. alternata的必要性.
科学领域:
- 菌类学 菌类学是指菌类学.
- 口腔病理学 口腔病理学
- 传染性疾病 传染性疾病
背景情况:
- 口腔粘膜的机会性真菌感染并不常见.
- Alternaria alternata是一种罕见的口腔感染原因,特别是在免疫能力强的个体中.
研究的目的:
- 报告一个独特的口腔穿孔病例,由Alternaria alternata感染引起.
- 为了强调诊断挑战和诊断的临床重要性,在口腔病理学中识别A. alternata.
主要方法:
- 持续的 palatal 疼痛的临床表现和成像发现表明骨吸收.
- 组织病理学检查 (血素-素,周期性酸-Schiff,免疫光染色) 和下一代测序用于真菌识别.
- 手术除和使用voriconazole的抗真菌治疗.
主要成果:
- 一名18岁的免疫能力强的男性出现了慢性口腔疼痛.
- 针对恶性瘤和结核病的初步调查没有得出结论.
- Alternaria alternata口腔感染的诊断通过先进的分子和组织学技术得到证实.
- 成功的治疗包括手术和长时间的伏利康纳治疗.
结论:
- 在口腔穿孔的差异诊断中,应考虑alternaria alternata,即使在免疫能力强的患者中也是如此.
- 这一案例凸显了罕见口腔真菌感染的综合诊断方法的重要性.
- 早期和准确的诊断对于有效的管理和预防并发症至关重要.
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