囊性纤维化中的纵向心理健康趋势
Michelle Hjelm1, Elizabeth Hente2, Jamie Miller3
1Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
概括
在囊性纤维化 (CF) 患者的常规心理健康查显示,随着时间的推移,焦虑和抑郁症状有所改善. COVID-19大流行并没有显著影响这些心理健康结果,突显了持续支持的必要性.
科学领域:
- 医学研究 医学研究
- 精神病学是一个精神病学.
- 肺部病理学 肺部病理学
背景情况:
- 2015年,精神健康查在囊性纤维化 (CF) 中心成为例行活动.
- 假设改善焦虑/抑郁和与疾病严重程度的关联.
- 旨在评估流行病和调节器使用对心理健康的影响.
研究的目的:
- 评估CF患者焦虑和抑郁症状的长期趋势.
- 检查心理健康查得分与CF疾病严重程度之间的关系.
- 评估COVID-19流行病和CFTR调节器治疗对心理健康的影响.
主要方法:
- 在6年内对150名患者 (12-22岁) 的回顾性图表审查.
- 利用了通用焦虑障碍-7 (GAD-7) 和患者健康问卷-9 (PHQ-9) 的查.
- 使用后勤回归和线性混合模型来分析查得分和临床变量.
主要成果:
- 随着时间的推移,焦虑和抑郁症的最小/无症状得分增加.
- 较高的GAD-7/PHQ-9分数与增加的精神健康访问和CF相关糖尿病 (CFRD) 有关.
- 更好的肺功能 (FEV1pp) 和调节器使用与较低的GAD-7/PHQ-9得分相关;大流行影响最小.
结论:
- 在大流行期间,心理健康查中断是最小的,症状得分稳定.
- 较高的心理健康得分与CFRD和更高的心理健康服务利用率相关.
- 持续的监测和支持对于面临健康和社会压力因素的CF患者至关重要.
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