已故捐赠者移植后的结果,使用带有边际 perfusion 参数的移植
Pranit N Chotai1, April Logan1, Jayanthan Subramanian1
1Division of Abdominal Transplantation, The Comprehensive Transplant Center, Department of General Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Transplantation proceedings
|July 1, 2023
概括
使用边缘 perfusion allografts 的脏移植显示,与良好 perfusion allografts 相比,移植器的存活率降低. 仔细选择可能使这些边缘在已故捐赠移植 (DDKT) 中使用.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 器官采购 器官采购
背景情况:
- 检查了已故捐赠人移植 (DDKT) 的结果.
- 专注于带有边缘 perfusion 参数的脏全移植.
研究的目的:
- 比较DDKT使用边缘 perfusion (MP) 和良好 perfusion (GP) 的结果.
- 评估移植的存活率和相关因素.
主要方法:
- 对1996-2017年DDKT受益人的回顾性分析.
- MP组:阻力指数 (RI) >0.4和流量 (F) <70毫升/分钟.
- 全科医生组:RI<0.4和F>70毫升/分钟;使用低温脉动性输液.
主要成果:
- 在MP组中,延迟移植功能 (DGF) 率较高 (19%与8%相比).
- 在MP (45%) 和GP (68%) 之间,5年后的移植存活率较低.
- 平均而言,MP接收者和捐赠者均年龄较大.
结论:
- 带有边缘 perfusion 参数的合移植显示DDKT后的移植存活率较低.
- 仔细的捐赠者和接受者评估可能允许利用一些边缘脏.
- 边缘脏的常规丢弃可能会根据严格的选择标准重新考虑.
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