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Updated: Jul 24, 2025

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蒂姆-3通过抑制NF-κB介导的炎症来防止西斯的毒性

Peiyao Li1, Xuemiao Li1, Wenbin Wu1

  • 1Joint National Laboratory for Antibody Drug Engineering, The First Affiliated Hospital of Henan University, Henan University, Kaifeng, 475004, P.R. China.

Cell death discovery
|July 1, 2023
PubMed
概括

蒂姆-3 (T细胞免疫球蛋白和粘素域含有蛋白3) 能防止西斯普拉丁诱导的损伤. 丢失Tim-3会加剧损伤,而溶性Tim-3会增加亡,这表明它通过抑制炎症和氧化应激来起保护作用.

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