改变的m6A修饰涉及YAP介导的亡反应在4-乙烯基二氧化诱导的卵子毒性

Yang Li1, Meifang Li2, Jian Liu1

  • 1Department of Gynaecology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510120, China.

概括

在老鼠中,暴露于4-乙烯基环二氧化物 (VCD) 诱导过早的卵巢缺陷 (POI) 通过减少卵巢卵泡和改变N6-甲基氨酸 (m6A) RNA修饰. 这项研究揭示了m6A修饰变化,为POI机制和潜在的治疗点提供了洞察力.

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