结合NAADP的蛋白质 - 将NAADP信号与癌症和免疫联系起来

Louisa D Heßling1, Berit Troost-Kind1, Mariella Weiß1

  • 1The Calcium Signaling Group, Dept. of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.

概括

尼古丁酸腺因二核酸 (NAADP) 信号传输涉及新发现的HN1L/JPT2和LSM12蛋白. 这些蛋白质在癌症和免疫路径中具有共同的致癌功能和作用,这表明了新的治疗点.

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