模两可的情感刺激的神经表现和新兴成年人对焦虑的弹性
Natalie M Saragosa-Harris1, João F Guassi Moreira1, Yael H Waizman1
1Department of Psychology, University of California Los Angeles, Los Angeles, CA 90095, United States.
Biological psychology
|July 2, 2023
概括
神经对模两可的表现,特别是在杏仁体中,与焦虑风险有关. 模糊和非威胁刺激之间的差异较小可能表明新兴成年人对焦虑的弹性.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 心理健康研究 心理健康研究
背景情况:
- 将模两可的刺激解释为威胁与焦虑障碍有关.
- 这种解释偏见在新兴的成年期至关重要,这是一个重要的生命过渡和社会导航时期.
- 处理模两可的神经基础及其与焦虑风险的关系仍然不清楚.
研究的目的:
- 调查神经对模两可的表示及其与威胁表示的相似性是否与新兴成年人的焦虑评估和症状相关.
- 探索杏仁体在处理模两可的社会线索中的作用.
- 识别与焦虑风险或弹性相关的神经标志物.
主要方法:
- 功能磁共振成像 (fMRI) 用于记录41名新兴成年人的大脑活动.
- 参与者看到了威胁 (愤怒),非威胁 (快乐) 和模糊 (惊) 的面部刺激.
- 代表性相似性分析 (RSA) 检查了杏仁体对面部刺激反应的模式相似性,并将其与焦虑测量和刺激评估相关联.
主要成果:
- 模糊和非威胁面孔之间的左桃体神经模式中更大的相似性 (较少的差异化) 与较低的同时出现的焦虑症状有关.
- 杏仁体内的试验级模式相似性预测了参与者对模两可的刺激的后续评估.
- 这些发现表明,神经对模两可的处理与焦虑脆弱性有关.
结论:
- 杏仁体内的模两可的神经表现与新兴成年期的焦虑风险和弹性有关.
- 对模两可的刺激与非威胁的刺激的神经反应的降低差异化可能是对焦虑的保护因素.
- 这项研究提供了对焦虑发展背后的神经机制的新见解,并提供了干预的潜在目标.
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