相关实验视频

Updated: Jul 24, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

Published on: October 6, 2014

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[以色列女性的BRCA中特定的基因变异的基因型-表型相关性]

Rachel Michaelson-Cohen1, Yael Laitman2, Inbal Kedar3

  • 1Medical Genetics Institute, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University of Jerusalem.

Harefuah
|July 2, 2023
PubMed
概括

与BRCA2携带者相比,BRCA1携带者面临更高的癌症风险和早期诊断. 特定的BRCA1变异,5382insC和185delAG分别显示出乳腺癌和卵巢癌的明显风险.

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