多发性硬化症和静脉血栓栓塞的发生率:系统性审查和元分析
Hamed Ghoshouni1, Behnam Shafaei1, Mahour Farzan1
1Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Journal of thrombosis and thrombolysis
|July 2, 2023
概括
多发性硬化症 (MS) 患者患静脉血栓塞栓症 (VTE) 的风险增加,包括深静脉血栓症 (DVT) 和肺血栓塞栓症 (PTE). 这一元分析证实MS与两倍高的VTE风险有关.
科学领域:
- 神经学 神经学
- 血管医学 血管医学
- 流行病学 流行病学
背景情况:
- 多发性硬化症 (MS) 越来越多地与严重的血管并发症有关,尤其是潜在致命的肺血栓栓塞 (PTE).
- 在系统性审查和元分析中存在一个显著的差距,用于量化静脉血栓塞栓症 (VTE),深静脉血栓症 (DVT) 和MS患者的PTE发病率 (pwMS).
结论:
- 尽管MS不是主要的风险因素,但它与VTE发病率的增加有显著的关联.
- 进一步的研究是有必要的,以调查MS及其治疗对VTE风险的影响,需要全面的混因素调整.
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