设计,合成和结构-活动关系 蛋白激酶CK2抑制剂的蛋白质激酶CK2抑制剂的设计,合成和结构-活动关系研究 含有纯素支架的蛋白质激酶CK2抑制剂的研究

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Updated: Jul 24, 2025

Identification of Novel CK2 Kinase Substrates Using a Versatile Biochemical Approach
11:11

Identification of Novel CK2 Kinase Substrates Using a Versatile Biochemical Approach

Published on: February 21, 2019

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Keiji Nishiwaki1, Shinya Nakamura1, Kenji Yoshioka1

  • 1Department of Pharmaceutical Sciences, Faculty of Pharmacy, Kindai University.

Chemical & pharmaceutical bulletin
|July 2, 2023
PubMed
概括

研究人员确定了针对蛋白激酶CK2 (CK2) 的基于纯素的新型抑制剂,这些抑制剂对癌症和COVID-19等疾病至关重要. 化合物12表现出显著的抑制活性,提供了新的治疗开发途径.

关键词:
这是一种CK2抑制剂.蛋白质激酶 CK2 的作用.纯氨酸的脚手架 纯氨酸的脚手架结构活动关系结构活动关系

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