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延迟过敏反应对含的对比剂:通过皮肤测试的诊断方法
Leonardo Bianchi1, Katharina Hansel1, Filippo Biondi1
1Section of Dermatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Contact dermatitis
|July 3, 2023
概括
皮肤测试能够准确诊断延迟过敏反应与含的对比剂 (ICM),识别iobitridol作为一个安全的替代方案,患者药物不良反应.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 放射学和成像学 放射学和成像学
背景情况:
- 对有的对比介质 (ICM) 的不良药物反应随着其在成像中的使用而增加.
- 延迟的过敏反应,通常对非离子单体化合物,使瘤学,心脏学和外科手术中的患者护理复杂化.
研究的目的:
- 预期评估皮肤测试对于诊断ICM延迟过敏反应的有用性.
- 评估iobitridol作为安全替代ICM的耐受性.
主要方法:
- 37名先前患有ICM过敏反应的患者接受了用罪祸首ICM和IOBITRIDOL进行贴片和皮内测试.
- 皮肤测试是在2020年至2022年之间进行的.
主要成果:
- 皮肤测试证实了51.4%的患者 (19/37) 的罪祸首ICM过敏,主要是通过贴片测试.
- 约比特里多尔仅在15.8% (3/19) 的敏感患者中显示出积极反应.
- 所有16名皮肤测试呈阴性IOBITRIDOL的患者都能耐受ICM,这表明其安全性.
结论:
- 皮肤检测,特别是贴片检测,是一种简单,经济有效和安全的方法来诊断ICM过敏症.
- 这种方法证实了致病性ICM,并将IOBITRIDOL确定为受影响患者的可行替代品.
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