在重症患者中治疗低血症
Max Melchers1,2, Arthur Raymond Hubert van Zanten1,2
1Department of Intensive Care Medicine, Gelderse Vallei Hospital, Ede.
Current opinion in critical care
|July 3, 2023
概括
低血症在重症患者中很常见,但缺乏支持补充来改善结果的证据. 目前的研究表明,它甚至可能是有害的,需要进一步调查风险和益处.
科学领域:
- 关键护理医学 关键护理医学
- 内分泌学 在内分泌学.
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 低血症影响55-85%的重症监护室 (ICU) 患者.
- 它与不良结果的关联可能是疾病严重程度的标志物,而不是直接原因.
- 目前的管理策略缺乏可靠的证据.
研究的目的:
- 审查危急病患者中低血症的机制.
- 综合当前关于管理严重疾病中低血症的证据.
- 了解低血症和临床结果之间的联系.
主要方法:
- 对现有文献进行系统审查.
- 对最近的研究和随机对照试验 (RCT) 的分析.
- 对病理生理机制的评估.
主要成果:
- 在重大出血中支持校正的证据较弱,需要进行RCT.
- 在心脏骤停中服用没有显示任何益处和潜在危害.
- 最近的研究表明,补充可能会伤害感染性ICU患者.
结论:
- 缺乏直接证据表明,在重症患者中补充可以改善治疗结果.
- 补充可能会对一些严重病患者,包括败血症患者有害.
- 需要进行前性研究,以澄清风险,益处和潜在机制.
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