在晚年,中风,抑郁和自我伤害
1Department of Psychiatry, Royal Perth Hospital, WA Centre for Health & Ageing, Medical School, University of Western Australia, Australia.
Current opinion in psychiatry
|July 3, 2023
概括
选择性血清素再吸收抑制剂 (SSRI) 不能有效地治疗或预防中风后的抑郁症. 在中风幸存者中,抗抑郁药的使用与更多的不良影响和自杀想法没有变化有关.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床试验 临床试验
背景情况:
- 脑卒中后抑郁症在12个月内影响了大约三分之一的幸存者.
- 抑郁症状可以持续或复发在30%的个人超过12个月.
- 卒中幸存者报告自杀想法比一般人群更频繁.
研究的目的:
- 审查选择性血清素再吸收抑制剂 (SSRI) 对中风后抑郁症和自杀念头的随机控制试验.
- 评估SSRI在中风幸存者的临床疗效和安全性.
主要方法:
- 系统审查最近随机的安慰剂受控试验.
- 对抑郁症患病率和自杀念头数据的分析.
- 评估与SSRI治疗相关的不良事件.
主要成果:
- 每天服用素 (20毫克6个月) 并没有改变中风幸存者的抑郁症患病率或自杀念头.
- 与安慰剂相比,抗抑郁药治疗导致更高的断药率,发作和骨折.
- 在SSRI治疗期间,没有观察到抑郁症状或自杀念头的显著减少.
结论:
- 目前的证据质疑SSRI在治疗和预防中风后抑郁症方面的有效性和安全性.
- 需要进一步的研究来澄清SSRI在严重中风病例或重大抑郁症发作中的疗效.
相关概念视频
Stress and Mental Health
186
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
186
Stress Prevention and Stress Management Techniques IV
49
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
49
Atherosclerosis IV: Nursing Management
23
Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...
23
Introduction to Stress and Lifestyle
147
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
147
Erikson's Theory on Socioemotional Development during Adulthood
151
Erik Erikson's theory of psychosocial development outlines a series of stages through which individuals progress across the lifespan. Each stage involves a psychosocial conflict that significantly influences personal growth and well-being. Three key stages — intimacy versus isolation, generativity versus stagnation, and integrity versus despair — highlight the developmental challenges faced in adulthood.
Intimacy Versus Isolation in Early Adulthood
Individuals in early...
Intimacy Versus Isolation in Early Adulthood
Individuals in early...
151
Stress Prevention and Stress Management Techniques VI
51
Adopting a healthier lifestyle often requires overcoming significant challenges, but leveraging psychological, social, and cultural resources can facilitate meaningful change. Effective self-change hinges on understanding and applying key tools such as motivation and goal setting, which help sustain efforts toward long-term health benefits.
Motivation and Self-Determination
Motivation, the driving force behind behavior, plays a pivotal role at every stage of the change process. The research...
Motivation and Self-Determination
Motivation, the driving force behind behavior, plays a pivotal role at every stage of the change process. The research...
51


