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Updated: Jul 24, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Published on: September 8, 2012

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CasDinG是一种5'-3' dsDNA和RNA/DNA基酶,具有三个辅助域,对于IV型CRISPR免疫力至关重要

Hannah Domgaard1, Christian Cahoon1, Matthew J Armbrust1

  • 1Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.

Nucleic acids research
|July 3, 2023
PubMed
概括

卡斯丁G蛋白对IV-A型CRISPR系统至关重要,它作为免疫所必需的DNA转位酶起作用. 它的N端域具有超越标准酶活性的独特功能,对细菌防御至关重要.

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