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Updated: Jul 24, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
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Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines

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通过罗催化剂对Podophyllotoxin衍生物分离合成的后期阶段功能化

Yue Zhao1,2, Yangpeng Shen1,2, Jian He1,2

  • 1School of Chinese Materia Medica, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Nanjing, 210023, P. R. China.

Chemistry (Weinheim an der Bergstrasse, Germany)
|July 3, 2023
PubMed
概括

研究人员使用催化剂开发了新的 podophyllotoxin 衍生物. 这项研究展示了从易于获得的天然产品中有效合成新化合物,扩大了药物化学的可能性.

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相关概念视频

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation02:17

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

Catalytic hydrogenation of alkenes is a transition-metal catalyzed reduction of the double bond using molecular hydrogen to give alkanes. The mode of hydrogen addition follows syn stereochemistry.
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
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