拉德克斯-UP测试核心:在社区参与的研究中获得COVID-19诊断,这些研究涉及贫困人口
Shanti Narayanasamy1,2, Timothy H Veldman3, Mark J Lee4
1Division of Infectious Diseases, Department of Medicine, Duke University, Durham, North Carolina, USA.
Journal of clinical microbiology
|July 3, 2023
概括
美国国立卫生研究院的RADx-UP计划成功地在服务不足的社区增加了COVID-19测试. 这个倡议提供了关键的资源和专业知识,证明了疫情期间有效的社区参与研究.
科学领域:
- 公共卫生 公共卫生
- 健康差距 研究 研究 研究 研究
- 流行病学 流行病学
背景情况:
- COVID-19不成比例地影响了服务不足的人群,SARS-CoV-2测试率较低.
- 国家卫生研究院 (NIH) 建立了诊断服务不足人口快速加速 (RADx-UP) 计划,以解决这一差距.
- RADx-UP代表了对健康差异和社区参与的研究的重大投资.
研究的目的:
- 描述RADx-UP测试核心 (TC) 在前两年的经验.
- 突出在服务不足的社区部署大规模的COVID-19诊断方面的挑战和见解.
- 为未来的流行病准备和公平的测试策略提供框架.
主要方法:
- RADx-UP测试核心为社区调查人员提供了科学专业知识和指导.
- 开发了适应性工具和框架,以支持社区发起的多样化测试策略.
- 实行了对测试策略和数据利用的持续监测.
主要成果:
- RADx-UP计划成功促进了基于社区的研究,以加强测试的获取和采用.
- 一个集中式协调中心提供了必不可少的工具,资源和多学科专业知识.
- 适应性和实时技术支持对于安全有效的测试部署至关重要.
结论:
- 通过集中资源支持的社区参与的研究,可以有效地增加流行病期间服务不足的人群的测试.
- 在未来的公共卫生危机中,RADx-UP模型为快速诊断部署提供了宝贵的教训.
- 公平获得测试至关重要,特别是对不成比例地受影响的社区来说.
相关概念视频
Principles of Disease Surveillance
127
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
127
Study Designs in Epidemiology
280
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
280
Community Based Intervention
66
Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
66
RACE - Rapid Amplification of cDNA Ends
6.4K
Rapid Amplification of cDNA Ends, or RACE, is one of the most effective methods to obtain a full-length cDNA from an mRNA sequence between a known internal region to the unknown sequence at the 5’ or 3’ end. The unknown region is cloned in the cDNA by a gene-specific primer that binds the known end, and a hybrid primer that attaches a predefined anchor sequence to the unknown end of the cDNA. The sequence in between is amplified by PCR with an anchor primer and a gene-specific...
6.4K


