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Updated: Jul 24, 2025

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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Published on: August 17, 2022

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醇衍生物与正位的结合会导致无脊椎动物Cys-loop受体的形状变化

Steven De Gieter1,2, Casey I Gallagher3, Eveline Wijckmans3

  • 1Center for Structural Biology, Vlaams Instituut voor Biotechnologie, Brussels, Belgium.

eLife
|July 3, 2023
PubMed
概括

研究人员研究了来自极端虫Alvinella pompejana的孤儿受体Alpo4. 冷-EM结构揭示了其连接物结合部位和离子孔的独特特征,为Cys-loop受体多样性提供了洞察力.

关键词:
这是一个cys-loop受体.膜蛋白质是一种膜蛋白质.分子生物物理学分子生物物理学氨酸联离子通道的离子通道.四分期变化的四分期变化.单颗粒冷电磁器 (Cryo-EM) 是一种单颗粒冷电磁器.这是一种固醇 (sterol) 固醇.结构生物学结构生物学

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