关于COVID-19和自身免疫性疾病的知识映射:视觉和文献分析分析
Youao Zhang1,2, Zixuan Jia3, Xu Xia4
1Department of Urology, The People's Hospital of Longhua, The Affiliated Hospital of Southern Medical University, Shenzhen, China.
Clinical and experimental medicine
|July 3, 2023
概括
这份图书统计分析显示,关于COVID-19和自身免疫性疾病 (AD) 的研究急剧增加. 关键领域包括免疫反应,特定的AD,治疗和自身免疫机制,指导未来的研究方向.
科学领域:
- 免疫学 免疫学 免疫学
- 类风湿病学 类风湿病学
- 传染性疾病 传染性疾病
- 图书统计学 图书统计学
背景情况:
- 越来越多的证据将COVID-19与自身免疫性疾病 (AD) 的发展或恶化联系在一起.
- 已经观察到关于COVID-19和ADs的研究出版物的显著增加.
- 没有全面的文献计量分析存在,以绘制COVID-19和AD研究的景观.
研究的目的:
- 进行关于COVID-19和自身免疫性疾病的科学文献的文献计量和视觉分析.
- 确定关键的研究趋势,热点和在这个领域有影响力的贡献者.
- 为了解COVID-19-AD关联提供对新兴研究方向的见解.
主要方法:
- 使用了科学网络核心集合SCI扩展数据库.
- 使用Excel 2019进行了使用文献计量分析.
- 应用可视化工具包括共发生 (COOC13.2),VOSviewer,CiteSpace和HistCite等.
主要成果:
- 总共有1736个相关出版物被确定,显示出日益增长的趋势.
- 美国在出版物方面领先,哈佛医学院是顶级机构,Yehuda Shoenfeld是最多产的作者,Frontiers in Immunology是领先的期刊.
- 研究热点包括免疫反应 (细胞因子风暴),特定的AD (狼,类风湿性关节炎,多发性硬化症),治疗方法 (氧化,rituximab),疫苗接种和自身免疫机制 (自身抗体,分子模拟).
结论:
- 关于自身免疫性疾病和COVID-19的出版率急剧增加.
- 本文献计量分析提供了对当前研究状况的全面概述.
- 这些发现突出了潜在的未来研究途径,重点关注COVID-19-AD关联的潜在机制和新的治疗策略.
相关概念视频
Autoimmune Disorders
517
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
517
Genome-wide Association Studies-GWAS
13.6K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
13.6K
Psychoneuroimmunology: Diabetes and Cancer
49
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
49


