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先进的心声回声技术 (AETs) 评估左心房结构和功能在具有抗性高血压的个体
Jonathan Batista Souza1, Márcio Gonçalves Sousa1, Antonio Gabriele Laurinavicius1
1Instituto Dante Pazzanese de Cardiologia, São Paulo, Brazil.
Echocardiography (Mount Kisco, N.Y.)
|July 3, 2023
概括
先进的心声回声技术揭示了抵抗性高血压 (RH) 的早期左心房功能变化. 这些方法,包括应变分析,可以检测RH和受控高血压 (CH) 患者的心房损伤.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
背景情况:
- 抗性高血压 (RH) 是一种复杂的高血压形式 (HTN),需要彻底评估.
- 评估左心房 (LA) 功能至关重要,但在RH管理中经常被忽视.
- 先进的心声回声技术 (AET) 提供了详细的LA评估的潜力.
研究的目的:
- 与受控高血压 (CH) 和正常血压 (N) 个体相比,研究耐性高血压 (RH) 患者的左心房 (LA) 形态功能变化.
- 评估AETs的实用性,包括应变分析和3D心声回声学,以检测这些变化.
主要方法:
- 96名成年患者被分为RH,CH和N组.
- 所有参与者都接受了AETs,特别关注LA菌株分析和3D心声回声学.
- 在这三个组中,LA的形态功能参数得到了定量评估.
主要成果:
- 与N和CH组相比,LA储菌株在RH患者中显著减少 (p < .001).
- LA导管应变显示了从N到CH到RH的下降梯度 (p = .015).
- 在CH患者中,LA收缩菌株高于N和RH组 (p = .02).
- 3D ECHO显示了N组和高血压组之间的LA体积差异 (p < .001),但CH和RH之间没有差异.
- 在N和RH之间,LA排空分数有所不同,N显示出更高的被动排空 (p = .02).
结论:
- 左心房表现出早期的功能变化,以应对高血压,可通过AETs检测.
- AETs,特别是LA菌株分析 (S-LA),可以在RH和CH患者中识别心房肌损伤的标志物.
- 这些发现突出了AETs在不同高血压表型中表征心房健康方面的作用.
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