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儿科非拉布多米索尔科马软组织瘤的放射治疗:综合性综述

Alper Kahvecioğlu¹, Melis Gültekin¹, Ferah Yıldız¹

¹Department of Radiation Oncology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.

The Turkish journal of pediatrics

|July 3, 2023

概括

根据风险调整的治疗方法是儿科非狂肌肉瘤软组织肉瘤 (NRSTS) 的标准. 低风险患者可能会省略辅助疗法,而中等和高风险患者可以从中受益,以减少复发.

科学领域:

儿科瘤学儿科瘤学
手术瘤学手术瘤学
辐射瘤学辐射瘤学

背景情况:

儿童非狂肌肉瘤软组织肉瘤 (NRSTS) 需要根据风险调整的治疗.
目标是将低风险病例的伤害降到最低,并在高风险病例中最大限度地获益.
本综述侧重于儿科NRSTS的预后因素,风险调整的治疗方法和放射治疗细节.

研究的目的:

审查预后因素,风险适应的治疗选择,以及儿科NRSTS的放射治疗特点.
根据最近的前性研究,突出目前的护理标准.
讨论新辅助和辅助疗法在NRSTS管理中的作用.

主要方法:

通过PubMed搜索找到的出版物的文献评论.
使用的关键词: "儿科软组织肉瘤", "非杆菌肉瘤", "软组织肉瘤 (NRSTS) "和"放射治疗".
精选出版物的详细评价.

主要成果:

根据风险适应的多模式治疗是儿科NRSTS的标准.
低风险患者可以安全地省略辅助化疗/放射治疗.
中期和高风险患者从辅助疗法中受益;新辅助治疗改善了无法切除的瘤的结果.
儿科放射治疗使用较小的场域和较低的剂量比成人方案,产生了很好的结果.

结论:

根据风险适应的多模式治疗是儿科NRSTS的标准.
对低风险患者来说,仅仅手术就足够了;辅助疗法是可选的.
辅助治疗对于中等/高风险患者来说至关重要,以减少复发.
新辅助疗法增强了不可切割的NRSTS的外科结果;未来的改善可能来自分子洞察力和向治疗.

关键词:

非拉布多米索尔科马软组织肉瘤儿科类肉瘤儿科类肉瘤辐射疗法辐射疗法肉瘤肉瘤是一种肉瘤.治疗治疗治疗治疗治疗治疗

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