晚期心脏磁共振成像在儿童多系统炎症综合征
Mustafa Argun1, Turgut Seber2, Sevgi Yaşar Durmuş3
1Department of Pediatric Cardiology, Health Sciences University School of Medicine, Kayseri City Training and Research Hospital, Kayseri.
The Turkish journal of pediatrics
|July 3, 2023
概括
儿童多系统炎症综合征可能导致心肌炎. 在康复后,患有肥胖的青少年可能会出现心脏纤维化,需要进一步研究以预测不良结果.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心血管成像 - 心血管成像
- 传染性疾病 传染性疾病
背景情况:
- 儿童多系统炎症综合征 (MIS-C) 可能导致心肌炎,从轻度病例到严重的心力衰竭.
- 虽然心脏参与通常在康复后会消失,但对心脏功能的长期影响仍然不清楚.
- 心脏磁共振成像 (MRI) 对于评估MIS-C后的心脏状况至关重要.
研究的目的:
- 通过在急性和恢复阶段进行心脏MRI来调查MIS-C后儿童的心脏参与.
- 为了确定潜在的风险因素和晚期 sequelae 的心肌炎在儿科患者.
主要方法:
- 心脏MRI对21名在MIS-C之后被诊断患有心肌炎的患者进行.
- 患者在疾病的急性和恢复阶段都接受了MRI.
- 与16名正常心脏MRI发现的健康对照进行了比较.
主要成果:
- 五名患者在MRI上表现出心脏纤维化,主要位于右心室后部插入点和中心室隔膜.
- 纤维化患者年龄较大,体重指数较高,白细胞和中性粒细胞数量变化.
- 在心脏纤维化患者中也观察到血尿和肌素水平升高.
结论:
- 青春期和肥胖被确定为MIS-C相关心肌炎后心脏纤维化发展的危险因素.
- 需要进一步的后续研究来预测和管理纤维化患者的潜在不良结果.
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