童年社区获得的黄金菌感染:一个多中心研究
Gülsüm İclal Bayhan1, Ayşe Kaman2, Esra Çakmak Taşkın3
1Department of Pediatric Infectious Disease, Yıldırım Beyazıt University Faculty of Medicine, Yenimahalle Educational and Training Hospital, Ankara.
The Turkish journal of pediatrics
|July 3, 2023
概括
儿童在社区获得的抗甲素黄金葡萄球菌 (CA-MRSA) 感染越来越令人担忧. 难民身份是唯一确定的风险因素,与敏感菌株相比,治疗结果相似.
科学领域:
- 传染性疾病 传染性疾病
- 儿科 儿科 儿科
- 微生物学 微生物学
背景情况:
- 越来越多的社区获得的甲素耐药黄金葡萄球菌 (CA-MRSA) 的全球流行率.
- 需要了解CA-MRSA患病率,风险因素和儿科患者的临床特征.
研究的目的:
- 调查MRSA在儿童社区获得的黄金色杆菌感染中的流行率.
- 为了确定与CA-MRSA感染相关的风险因素.
- 描述CA-MRSA在儿科患者中的临床特征.
主要方法:
- 多中心研究,具有前性和后性组成部分.
- 包括小儿病患者 (≥3个月至≤18岁) 与社区获得的金黄色细菌感染.
- 数据收集包括医疗/微生物学记录和有关风险因素的家长问卷;CA-MRSA病例与甲素敏感金黄色菌 (MSSA) 病例相比.
主要成果:
- 确定了334例儿科金黄色细菌感染;58例 (17.4%) 是CA-MRSA.
- 在CA-MRSA组中观察到更高的难民率.
- 在CA-MRSA和MSSA组之间,暴露风险,治疗方法或结果没有显著差异.
结论:
- 难民身份成为儿童中CA-MRSA的潜在风险因素.
- 除了难民身份之外,还发现了有限可靠的临床或流行病学风险因素.
- 对于疑似葡萄球菌感染的实证抗生素选择,应考虑当地的CA-MRSA流行.
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