门关节的内镜二氧化碳吸入耐受性测试用于门功能下降:试点和可行性研究
Akiko Toshimori1, Mayo Tanabe1, Yuto Shimamura1
1Digestive Disease Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.
Annals of gastroenterology
|July 3, 2023
概括
阳门功能随着年龄的增长而下降,正如使用内镜压力研究综合系统 (EPSIS) 对老年人下方直肠压力测量所表明的那样. 这种测试可能有助于诊断与年龄相关的直肠低功能.
科学领域:
- 胃肠病学 胃肠病学
- 身体生理学 身体生理学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 直肠功能自然会随着年龄的增长而下降.
- 内镜压力研究综合系统 (EPSIS) 是胃食道逆流病的已知诊断工具.
- 它在评估直肠功能,特别是老年人的实用性,仍然未被探索.
研究的目的:
- 评估EPSIS在评估与年龄相关的门功能变化中的适用性.
- 为了比较年轻和老年患者组之间的EPSIS直肠压力测量.
- 探索EPSIS作为下胃肠道疾病的潜在诊断工具.
主要方法:
- 一项试点,单一中心,回顾性研究,采用前性收集数据 (2021年12月-2022年3月).
- 在结肠镜检查期间,EPSIS涉及CO2灌注,直到门气体泄漏,测量最大直肠压力 (EPSIS-RPmax).
- 在患者<80岁和≥80岁之间比较EPSIS-RPmax.
主要成果:
- 这项研究包括30名患者.
- 与年轻人 (18.7 mmHg) (P<0.001) 相比,老年组的EPSIS-RPmax中位数显著较低 (9.8 mmHg),而年轻组的EPSIS-RPmax中位数显著较低 (P<0.001).
- 这表明生理性直肠功能与年龄相关的下降.
结论:
- 使用EPSIS测量最大直肠压力反映了与年龄相关的直肠功能下降.
- 作为查和诊断直肠低功能的工具,EPSIS显示出希望.
- 未来的研究应该调查EPSIS负载测试以量化功能衰退.
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