身体活动和坐着与代谢综合征和青少年高血糖参数的关联 - BRAMS儿科研究
Talita Oliveira Silva1, Marina Maintinguer Norde1, Ana Carolina Vasques1
1Laboratory of Diabetes and Metabolism Investigation (LIMED), School of Medical Sciences of the State University of Campinas (FCM-UNICAMP), Campinas, SP, Brazil.
Frontiers in endocrinology
|July 3, 2023
概括
每天坐8个小时以上的青少年增加了代谢综合征的几率. 促进体育活动 (PA) 可以改善青少年的胰岛素敏感性和代谢健康.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 代谢健康 代谢健康
- 青少年健康 青少年健康
背景情况:
- 肥胖和代谢综合征 (MetS) 对青少年健康构成重大风险.
- 行为干预,特别是体力活动 (PA),是青少年MetS的首选治疗方法.
研究的目的:
- 调查青少年体力活动 (PA) 和坐着时间与MetS之间的联系.
- 通过一套全面的代谢健康参数来检查PA和坐时间之间的关系.
主要方法:
- 来自巴西儿科代谢综合征研究 (BRAMS-P) 的448名巴西青少年 (10-19岁) 的截面研究.
- 数据通过生活方式问卷,国际体育活动问卷对PA和坐时间以及临床测量 (人体测量,血压,血液标志物) 收集.
- 使用HOMA-IR评估胰岛素耐药性,其中一个亚样本接受了高血糖.
主要成果:
- 青少年花费超过8小时的时间坐着有显著更高的MetS的几率 (OR=2.11).
- 增加的坐时间与更高的BMI,腰围,身体脂肪百分比和更差的血液脂质概况相关.
- 中度至高的PA与改善的胰岛素敏感性 (rho=0.29,p=0.047) 有中度和正相关.
结论:
- 限制坐着时间对于改善青少年代谢健康至关重要.
- 定期体育活动与胰岛素敏感性增强有关,可以预防所有青少年的不良代谢结果,包括体重正常的青少年.
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