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量身定制的ASD破坏稳定 - - 以基烯基纤维素平衡保质期稳定性和溶解性能

Christian Luebbert1, Edmont Stoyanov2

  • 1amofor GmbH, Otto-Hahn-Str. 15, Dortmund D-44227, Germany.

International journal of pharmaceutics: X
|July 3, 2023
PubMed
概括

三级无形固体分散 (ASDs) 提高了药物溶解度,但面临一个权衡. 优化聚合物比率的稳定性在含有 fenofibrate 或 simvastatin 的 ASD 中可以降低溶解性能.

关键词:
无形固体的分散性固体.结晶化 结晶化 结晶化溶解行为是溶解行为.氧烯基纤维素的含量是多少长期稳定性的长期稳定性混合性 混合性 混合性在PC-SAFT中使用.可溶性 可溶性 溶性超和 超和 超和

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