在尼日利亚男性中,丸激素-雌激醇比率和一些人体测量和代谢参数之间的关系
Holiness Stephen Adedeji Olasore1, Tolulope Adejoke Oyedeji1, Matthew Olamide Olawale1
1Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Idi Araba, Lagos, Nigeria.
Metabolism open
|July 3, 2023
概括
尼日利亚男性的-雌激素 (T/E2) 比率与体重和身高有关,但与BMI或腰围无关. 这种荷尔蒙比率也与禁食血糖,肌素和尿素水平相关.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 人体生理学 人体生理学
背景情况:
- 性激素水平在调节男性的新陈代谢过程中发挥作用.
- 肥胖和2型糖尿病等代谢障碍在尼日利亚正在增加.
- 血清丸激素与雌激醇的比率可能与男性的这些代谢障碍有关.
研究的目的:
- 调查尼日利亚男性-雌激素 (T/E2) 比率和人体测量测量之间的关系.
- 在这个人群中检查T/E2比率和关键代谢参数之间的关联.
- 了解尼日利亚男性对代谢健康的潜在荷尔蒙影响.
主要方法:
- 招募了85名尼日利亚成年男性进行数据收集.
- 测量的人类测量数据包括体重,身高,BMI和腰围.
- 评估了总体的血水平,雌激素,禁食血糖,肌素,尿素,高密度胆固醇,总胆固醇和甘油三.
主要成果:
- 在T/E2比和体重 (r=-0.265) 和身高 (r=-0.288) 之间观察到负相关性.
- T/E2比率与空腹血糖 (r=0.219),肌素 (r=0.992) 和尿素 (r=0.152) 有正相关性.
- 在T/E2比率和体重,身高,禁食血糖,肌素和尿素之间发现了显著的相关性.
结论:
- 在尼日利亚男性中,T/E2比与特定的人类测量 (体重,身高) 和代谢参数 (禁食血糖,肌素,尿素) 有显著的相关性.
- 在T/E2比率和BMI,腰围,高密度胆固醇或甘油三之间没有发现显著的相关性.
- 这些发现凸显了性激素平衡在尼日利亚男性代谢调节中的潜在作用.
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