相关实验视频

Updated: Jul 24, 2025

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

肉中的免疫反应和组织学变化接种了Mycoplasma gallisepticum疫苗的

S Muofaq Khalaf¹, A Jawad Ali¹

¹Department of Pathology and Poultry Diseases, Veterinary Medicine University of Baghdad, Baghdad, Iraq.

Archives of Razi Institute

|July 3, 2023

概括

用活体和非活化Mycoplasma gallisepticum (MG) 疫苗接种肉小显著提高了抗体标位,并刺激了免疫器官. 这种联合疫苗接种策略在增强幼体内免疫反应方面被证明是最有效的.

科学领域:

兽医免疫学兽医免疫学
禽类的健康禽类的健康
细菌学细菌学是一门学科.

背景情况:

菌菌 (Mycoplasma gallisepticum,MG) 是一个重要的家禽病原体.
像Mycoplasma这样的没有细胞壁的细胞核生物在疾病控制中提出了独特的挑战.
有效的疫苗接种策略对于在肉中管理MG至关重要.

研究的目的:

为了评估活体免疫反应和免疫器官刺激,用活体和/或非活化Mycoplasma gallisepticum (MG) 疫苗接种的 brojler.
为了比较单个 (活体或无活体) 与联合疫苗接种方案的疗效.
为了评估接种疫苗后免疫器官的组织病理变化.

主要方法:

130只一天大的肉被分为四组:活体MG疫苗,无活化的MG疫苗,活体和无活化的MG疫苗组合,以及对照组.
在21日和35日使用酶相关免疫吸收试验 (ELISA) 测量了抗体 (Ab) 标位.
在第35天,对Fabricius的囊和脏进行了组织病理学评估.

主要成果:

所有接种疫苗的群体在第21天和第35天显示出与对照组相比显著更高的Ab位数.
活疫苗和非活化疫苗组合 (G3) 在两天表现出最高的Ab位数.
组织病理学分析显示,在接种疫苗的组中,免疫刺激,包括囊中的淋巴细胞增生和中的淋巴细胞增生,特别是G3.

结论:

与活体和非活化Mycoplasma gallisepticum (MG) 疫苗的联合接种在增强幽默免疫力和刺激肉小的免疫器官方面非常有效.
与单个疫苗类型相比,联合疫苗策略导致更高的抗体产生和免疫器官反应.
用MG疫苗接种引发了显著的,剂量依赖的免疫反应和Fabricius的囊和脏的组织病理变化.

关键词:

活体疫苗是一种活体疫苗.疫苗疫苗疫苗疫苗菌细胞菌菌体 (Mycoplasma gallisepticum) 已经成为一种常见的疾病.

更多相关视频

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle

Published on: July 11, 2015

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

相关概念视频

Vaccinations

Vaccinations

Immunological Memory

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...