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Updated: Jul 24, 2025

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
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Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

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作为向放射性核酸治疗的共价蛋白增强抗瘤效果

Paul C Klauser1,2, Shalini Chopra1,2,3, Li Cao1,2

  • 1Department of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California San Francisco, San Francisco, California 94158, United States.

ACS central science
|July 3, 2023
PubMed
概括

这项研究引入了癌症的第一个共价蛋白放射性核素疗法 (TRT). 这种新的方法通过形成不可逆转的纽带来提高瘤向和疗效,提高安全性和治疗结果.

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