与精准医学中的伦理问题和风险相关的患者观点:系统性审查
Lawko Ahmed1, Anastasia Constantinidou1, Andreas Chatzittofis1,2
1Medical School, University of Cyprus, Nicosia, Cyprus.
Frontiers in medicine
|July 3, 2023
概括
患者担心隐私,成本以及精准医学中的歧视. 通过教育和政策解决这些道德风险对于患者的信任和有效的临床实践至关重要.
科学领域:
- 基因组学就是基因组学.
- 生物伦理学生物伦理学
- 医疗信息学 医疗信息学
背景情况:
- 精准医学的进步,包括下一代测序和人工智能,引发了伦理方面的担忧.
- 虽然专业人士了解这些风险,但患者对精准医学的伦理问题的看法却鲜为人知的.
- 这一系统性审查侧重于患者对精准医学道德风险的态度.
研究的目的:
- 系统地审查和综合患者对准确医学相关的伦理考虑和风险的观点.
- 从患者的角度来看,确定关键的伦理主题,以确定准确医学的实施.
主要方法:
- 在PubMed中从2012年1月到2023年4月进行了系统的文献搜索.
- 文章的选择和评价遵循了PRISMA指南和乔安娜·布里格斯研究所的标准.
- 在选了914篇初始文章后,包括了24项相关的定性研究.
主要成果:
- 关于患者关注的八个主要主题出现了:数据隐私/安全,经济影响,心理社会伤害,歧视风险,知情同意挑战,对提供者/研究的不信任,诊断准确性问题以及医生患者关系的改变.
- 患者在精准医学中发现了重要的伦理和风险相关问题.
- 关键问题围绕数据安全,财务影响和潜在的歧视.
结论:
- 患者在精准医学中的伦理问题和感知风险是重要的,需要注意.
- 解决这些问题需要患者教育,进一步研究和明确的政策制定.
- 了解患者的观点对于临床医生来说至关重要,以有效地管理临床实践中的问题.
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