正常盐水与血液对经历神经外科手术的患者凝血和代谢状态的影响
Vandna Arora1, Akanksha Khatri1, Renu Bala1
1Department of Anaesthesiology, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India.
Asian journal of neurosurgery
|July 3, 2023
概括
正常的盐水和PlasmaLyte在神经外科患者中显示了类似的凝血概况. 与正常盐水相比,PlasmaLyte提供了更好的酸和功能.
科学领域:
- 麻醉学 麻醉学
- 神经外科 神经外科
- 密集护理医学 密集护理医学
背景情况:
- 对于神经外科患者来说,手术内液体的选择至关重要,以保持大脑输液并避免胀.
- 正常的盐水 (NS) 可以导致高性代谢酸和凝血病.
- 像PlasmaLyte (PL) 这样的平衡晶体可能会提供更好的代谢特征.
研究的目的:
- 为了比较NS与PL对神经外科患者凝血概况的影响.
- 评估这些液体对酸和脏参数的影响.
主要方法:
- 对100名成年神经外科患者进行前性,随机,双盲研究.
- 患者在手术期间和术后4小时内接受NS或PL治疗.
- 测量了血红蛋白,血红素,凝血概况 (PT,PTT,INR),血清化物,pH,血尿素和肌素.
主要成果:
- 在NS和PL组之间凝血参数没有显著差异.
- 与PL组相比,NS组的pH值在手术后4小时显著降低.
- 在NS组中,手术后血尿素,血清肌素和血清的升高.
结论:
- 术内NS和PL在神经外科手术过程中产生了可比的凝血概况.
- 在这种患者群体中,PlasmaLyte的使用与与正常盐水相比,与改善的酸平衡和功能有关.
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