治疗儿科功能性腹痛疾病的非药理学方法
Partha Sarathi Chakraborty1, Rhea Daniel1, Fernando A Navarro1
1Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, United States.
Frontiers in pediatrics
|July 3, 2023
概括
儿童的功能性腹痛障碍 (FAPD) 与大脑-肠道相互作用有关. 这篇评论探讨了非药物治疗方法,如饮食,微生物组操纵和FAPD的心理治疗方法.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 神经胃肠病学 神经胃肠病学
- 大脑与肠道的相互作用
背景情况:
- 功能性腹部疼痛障碍 (FAPDs) 影响到25%的美国儿童.
- 人们越来越多地把FAPD理解为大脑与肠道相互作用的障碍.
- 病理生理学涉及肠道运动,内脏过敏,微生物组失调以及心理因素.
研究的目的:
- 对儿童的FAPD进行非药理干预的审查.
- 总结饮食,基于微生物组和心理治疗方法.
- 突出需要对这些疗法进行基于证据的研究.
主要方法:
- 对FAPDs的非药物治疗方法的文献综述.
- 干预措施的分类为饮食,微生物组操纵和心理方法.
- 包括来自对补充和替代医学使用调查的数据.
主要成果:
- 非药物治疗策略包括饮食改变,微生物组调节 (益生菌,益生菌,FMT) 和心理治疗 (CBT,催眠疗法).
- 大多数患者 (96%) 使用补充和替代医学.
- 仅有有限的数据支持许多已审查的治疗方法的疗效.
结论:
- 非药物干预为儿科FAPD提供了潜在的治疗途径.
- 进一步的大规模随机对照试验对于确定疗效和指导临床实践至关重要.
- 解决大脑-肠轴组件对于管理FAPD至关重要.
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