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儿科猫头痛的替代性精神药物治疗方法:一个回顾性分析
Joshua R Smith1,2, Isaac Baldwin3, Tasia York1
1Division of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center at Village of Vanderbilt, Nashville, TN, United States.
Frontiers in child and adolescent psychiatry
|July 3, 2023
概括
儿科性可以有效地用替代药物治疗,如类药物,抗药和非典型抗精神病药物,当洛拉泽帕姆无法使用或电疗法 (ECT) 不可能时. 在一项对31名儿童的研究中,这些治疗方法显著改善了触动性症状.
科学领域:
- 儿童和青少年精神病学
- 药理学 药理学是指药理学的学科.
- 神经学 神经学
背景情况:
- 儿科性猫症带来了治疗挑战,具有有限的选择,如电疗法 (ECT) 或洛拉泽帕.
- 洛拉泽帕姆的可访问性和ECT的立法/耻辱障碍需要替代治疗策略.
研究的目的:
- 评价儿童白内障的替代性精神药物治疗方法的疗效和安全性.
- 为了确定有效的非洛拉泽帕姆治疗选择,为儿童诊断出白内障.
主要方法:
- 对31名儿科患者 (18岁以下) 进行了回顾性分析,这些患者接受了非洛拉泽帕姆类精神药物治疗.
- 使用布什 - 弗朗西斯卡塔托尼评分尺度 (BFCRS),卡纳尔卡塔托尼严重程度尺度 (KCS),卡纳尔卡塔托尼检查 (KCE) 和临床全球印象改善 (CGI-I) 进行评估.
主要成果:
- 在治疗后观察到BFCRS,KCS和KCE得分的显著降低 (p < 0.001).
- 80%的患者表现出改善,68%需要额外的药物,如抗药,NMDA受体对抗剂,阿里皮普拉或克洛札.
- 克罗纳泽巴姆或泽巴姆使患者稳定,表明除洛拉泽巴姆以外的二类药物的有效性.
结论:
- 替代性药理干预措施,包括二,酸,NMDA受体对抗剂和非典型抗精神病药物,对于儿科猫是安全有效的.
- 这些发现支持在标准选择有限的情况下使用非洛拉泽治疗方法,改善患者的治疗结果.
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