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体质指数对新辅助化疗后病理反应的影响:I-SPY 2试验结果

Haiyun Wang¹, Douglas Yee², David Potter²

¹Cancer Care Associates.

Research square

|July 3, 2023

概括

身体质量指数 (BMI) 在接受新辅助化疗的高风险乳腺癌妇女中没有显著影响病理完整反应 (pCR) 率. 在I-SPY 2试验中,生存结果在BMI类别之间也没有显著差异.

科学领域:

在瘤学瘤学.
临床试验临床试验
流行病学流行病学

背景情况:

增加的体重指数 (BMI) 与乳腺癌患者的较差结果有关.
I-SPY 2试验研究了高风险乳腺癌的新辅助疗法.

结论:

身体质量指数 (BMI) 似乎不会影响这种高风险乳腺癌队列中对新辅助化疗的病理完整反应 (pCR).
在BMI类别之间没有观察到无事件生存 (EFS) 或总生存 (OS) 的显著差异.
这些发现表明,标准的BMI分类可能不是这个特定患者群体治疗反应的显著预后因素.

关键词:

身体质量指数 (BMI) 是指身体质量指数.乳腺癌乳腺癌乳腺癌新辅助化学疗法新辅助化学疗法肥胖问题肥胖问题病理学的完整反应反应.

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