压力后的神经敏感性预测无症症状:为期2年的多波长度研究
David Pagliaccio1, Diego Pizzagalli2, Randy Auerbach
1New York State Psychiatric Institute/Columbia University.
Research square
|July 3, 2023
概括
急性压力会影响青少年大脑对奖励和损失的反应. 减少对奖励的右腹条纹体反应预测了生活压力增加的无症严重程度,突出了抑郁症风险机制.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 发展心理学 发展心理学
背景情况:
- 动物模型将急性压力与损害的奖励/惩罚神经功能和无情感联系起来.
- 人类对压力诱导的神经变化和无情感的研究是有限的,阻碍了对情感障碍风险的理解.
- 无情是情绪障碍的一个关键症状,需要进一步研究与压力相关的神经机制.
结论:
- 这些发现与动物模型一致,表明青少年中压力诱导的无症的神经机制.
- 独特的神经通路可能是压力相关的抑郁和焦虑症状出现的基础.
- 在急性压力后对奖励和损失的神经反应可能作为情感障碍风险的生物标志物.
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