Search research articles

关于 JoVE

概览领导团队博客 JoVE 帮助中心

作者

出版流程编辑委员会范围与政策同行评审常见问题投稿

图书馆员

用户评价订阅访问资源图书馆顾问委员会常见问题

研究

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments 存档

教育

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual 教师资源中心教师网站

使用条款与条件

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序

Same author

SCS: cell segmentation for high-resolution spatial transcriptomics.

Nature methods·2023

Same author

UNIFAN: A Tool for Unsupervised Single-Cell Clustering and Annotation.

Journal of computational biology : a journal of computational molecular cell biology·2022

Same author

Unsupervised cell functional annotation for single-cell RNA-seq.

Genome research·2022

Same author

TraSig: inferring cell-cell interactions from pseudotime ordering of scRNA-Seq data.

Genome biology·2022

Same author

Identifying signaling genes in spatial single-cell expression data.

Bioinformatics (Oxford, England)·2020

Same author

Quantifying the Impact of Non-coding Variants on Transcription Factor-DNA Binding.

Research in computational molecular biology : ... Annual International Conference, RECOMB ... : proceedings. RECOMB (Conference : 2005- )·2017

Same journal

Genetic Impacts on Variability of Body Fat Distribution Uncover Gene-Environment and Gene-Gene Interactions.

bioRxiv : the preprint server for biology·2026

Same journal

16S ribosomal RNA modification drives transcript-specific translation efficiency.

bioRxiv : the preprint server for biology·2026

Same journal

FlcE latches onto the FliL-stator complex to turbocharge flagellar motility in <i>Borrelia burgdorferi</i>.

bioRxiv : the preprint server for biology·2026

Same journal

Synaptic pruning, myelination and the emergence of psychiatric disorders in late adolescence.

bioRxiv : the preprint server for biology·2026

Same journal

Structural and functional insights into the Rcs phosphorelay.

bioRxiv : the preprint server for biology·2026

Same journal

The structural basis of RanGAP1 regulation and catalysis in nuclear transport.

bioRxiv : the preprint server for biology·2026

查看所有相关文章

Search research articles

相关实验视频

Updated: Jul 24, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Published on: July 6, 2022

SCS:用于高分辨率空间转录组学的细胞细分.

Hao Chen¹, Dongshunyi Li¹, Ziv Bar-Joseph^1,2

¹Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

bioRxiv : the preprint server for biology

|July 3, 2023

概括

此摘要是机器生成的。

空间转录组学方法现在提供亚细胞分辨率. 我们的新工具SCS通过结合成像和测序数据来提高细胞细分的准确性,以获得更好的RNA定位洞察力.

科学领域:

分子生物学分子生物学
基因组学就是基因组学.
生物信息学是一种生物信息学.

更多相关视频

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging

Published on: April 30, 2019

Spatially Compact Arrangement of Larval Zebrafish Sections for Spatial Transcriptomic Analysis

Spatially Compact Arrangement of Larval Zebrafish Sections for Spatial Transcriptomic Analysis

Published on: May 16, 2025

相关实验视频

Last Updated: Jul 24, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Published on: July 6, 2022

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging

Published on: April 30, 2019

Spatially Compact Arrangement of Larval Zebrafish Sections for Spatial Transcriptomic Analysis

Spatially Compact Arrangement of Larval Zebrafish Sections for Spatial Transcriptomic Analysis

Published on: May 16, 2025

背景情况:

空间转录学使我们能够理解组织组织和细胞相互作用.
目前的平台往往缺乏蜂分辨率,限制了洞察力.
新兴的亚细胞分辨率技术在细胞细分和点分配方面面临挑战.

结论:

SCS推进了细胞细分,用于亚细胞空间转录学.
改善了细胞内RNA局部化的分析.
有助于更深入地了解细胞架构和功能.