帕克斯洛维德 (尼马特里尔维尔/里托纳维尔) 对N3C医院住院和死亡的有效性:一个向试验仿真研究
medRxiv : the preprint server for health sciences
|July 3, 2023
概括
这项研究表明,Paxlovid (nirmatrelvir/ritonavir) 在高风险的COVID-19患者中显著减少住院和死亡. 早期使用Paxlovid治疗对于预防严重后果至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- COVID-19继续构成威胁,需要有效的治疗来预防严重疾病,住院和死亡.
- 帕克斯洛维德 (nirmatrelvir/ritonavir) 是一种抗病毒药物,已被授权用于治疗COVID-19的紧急使用.
结论:
- 帕克斯洛维德在现实环境中有效预防高危COVID-19患者住院和死亡.
- 这些发现支持使用Paxlovid作为在符合条件的人群中管理COVID-19的关键干预措施.
- 在各种敏感性分析中,结果一致,加强了该药物的疗效.
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