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Updated: Oct 3, 2026

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection
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Published on: June 5, 2021

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一种半定量,快速的SARS-CoV-2血清分析预测了中和抗体水平

Alena J Markmann1, D Ryan Bhowmik2, Baowei Jiang3

  • 1Department of Medicine, Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill NC 27599, USA.

bioRxiv : the preprint server for biology
|July 3, 2023
PubMed
概括

一种新的半定量横向流量测定 (sqLFA) 准确检测针对SARS-CoV-2的功能中和抗体. 这种快速测试与中和抗体水平相关,有助于决定COVID-19疫苗接种和治疗方法.

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相关概念视频

Enzyme-Linked Immunosorbent Assay01:33

Enzyme-Linked Immunosorbent Assay

In 1971, Peter Perlman and Eva Engvall developed an Enzyme-linked immunosorbent assay (ELISA or EIA). ELISA differs from western blot in that the assays are conducted in microtiter plates or in vivo rather than on an absorbent membrane.
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen.  Enzyme-substrate reaction allows the antigen to be visualized or quantified.