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Updated: Jul 24, 2025

Author Spotlight: A Bicelle Crystallization Setup for ABC Transporter Membrane Proteins to Advance Drug Development
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Author Spotlight: A Bicelle Crystallization Setup for ABC Transporter Membrane Proteins to Advance Drug Development

Published on: August 25, 2023

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不对称的形状和脂质相互作用塑造了异构体ABC载体的ATP合循环

Qingyu Tang, Matt Sinclair, Hale S Hasdemir

    bioRxiv : the preprint server for biology
    |July 3, 2023
    PubMed
    概括

    这项研究揭示了像BmrCD这样的ABC输送器中的不对称构造如何驱动催化不对称,并塑造运输能量. 脂质相互作用调节这些状态,影响整体的运输机制.

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