患有抑郁症的患者的性别特异性性功能障碍.
Xinyu Liu1, Zizhao Feng1, Britta Galling2,3
1The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Frontiers in psychiatry
|July 3, 2023
概括
性功能障碍 (SD) 影响超过60%的大型抑郁症 (MDD) 患者,女性患病率更高. 女性性别,45岁以上,低收入,惰和身体症状是MDD中SD的关键风险因素.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 重度抑郁症 (MDD) 是一种普遍存在的心理健康状况.
- 性功能障碍 (SD) 是MDD患者常见的,经常使人衰弱的并发症.
- 了解导致MDD中SD的因素对于改善患者的治疗结果至关重要.
研究的目的:
- 在被诊断为患有严重抑郁症 (MDD) 的患者中调查性功能障碍 (SD) 的患病率和严重程度.
- 确定与这种患者群体中SD的发生和严重程度相关的人口和临床因素.
- 专门研究性别对MDD个体中SD呈现的影响.
主要方法:
- 一组273名MDD患者 (174名女性,99名男性) 接受了社会人口统计和临床评估.
- 使用了包括ASEX,QIDS-SR16,GAD-7和PHQ-15在内的标准化仪器.
- 统计分析包括单变量分析,t测试,奇平方测试,费舍尔精确测试和后勤回归.
主要成果:
- 在MDD队列中观察到SD的高患病率 (61.9%),女性的患病率 (75.3%) 与男性 (38.4%) 相比显著更高.
- 女性性别,45岁或以上的年龄,低月收入 (≤750美元),增长的惰和体质症状被确定为SD的重要风险因素.
- 女性患者表现出更严重的SD (ASEX评分21.1±5.4) 比男性患者 (ASEX评分17.1±4.6).
结论:
- 在患有MDD的患者中,SD的患病率和严重程度存在显著的基于性别的差异.
- 在MDD中,SD的关键风险因素包括女性性别,年龄较大,收入较低,惰和体质症状负担.
- 这些发现强调了在MDD患者的特定亚组中对SD进行有针对性的查和管理的需要.
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