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在瘤微环境中,重振耗尽的CD8+ T细胞的策略

Qianting Guan1, Meiwen Han1, Qinghao Guo1

  • 1Department and Institute of Infectious Disease, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Frontiers in immunology
|July 3, 2023
PubMed
概括

重振耗尽的CD8+ T细胞 (CD8+ TEXs) 对于癌症免疫疗法至关重要. 目前的策略旨在改善它们对瘤的功能,为耐受免疫检查点封锁的患者提供新的希望.

关键词:
细胞因子疗法 细胞因子治疗表观遗传疗法是一种表观遗传疗法.已经耗尽的CD8 + T细胞.免疫检查点封锁封锁基于新陈代谢的疗法基于转录因子的疗法瘤微环境是一个微环境.

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