探索血液学参数与2型糖尿病中早期糖尿病病的相关性
Susmitha Chollangi1, Nikunj K Rout2, Sudhir K Satpathy1
1Department of General Medicine, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology Deemed to be University, Bhubaneswar, IND.
Cureus
|July 3, 2023
概括
血液学标志物中性粒细胞与淋巴细胞比率 (NLR) 和红细胞分布宽度 (RDW) 在早期糖尿病病中升高. 在2型糖尿病患者中,NLR比RDW更有效地预测早期损伤.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 内分泌学 在内分泌学.
- 血液学 血液学 血液学
背景情况:
- 糖尿病病是2型糖尿病 (DM) 控制不良的常见并发症.
- 无法控制的DM会通过细胞内血管变化和益菌性反应引起损伤.
- 早期发现糖尿病病对于管理这种疾病至关重要.
研究的目的:
- 调查早期糖尿病脏病患者血液学标志物和微专尿之间的关联.
- 为了比较中性粒细胞与淋巴细胞比率 (NLR) 和早期糖尿病病的红细胞分布宽度 (RDW) 的预测值.
主要方法:
- 一项涉及90名2型糖尿病患者的横截面研究,根据微专尿分为两组.
- 在各组之间测量和比较NLR和RDW水平.
- 接收机操作特征 (ROC) 曲线分析,以评估NLR和RDW的预测性能.
主要成果:
- 在患有和没有微专尿的患者之间观察到NLR (p = 0.001) 和RDW (p = 0.015) 的显著差异.
- 在ROC分析中,NLR的0.814和RDW的0.656的曲线下面的面积用于预测微专尿.
- 与RDW相比,NLR在早期糖尿病病中表现出更强的预测能力.
结论:
- 升高的NLR和RDW表明2型糖尿病患者的早期糖尿病病.
- 与RDW相比,NLR作为更有效的血液学标志物用于预测早期糖尿病病.
- 这些发现强调了简单的血液学标记在糖尿病病的早期查和管理中的潜力.
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