与年龄相关的横向变化在成长中的老鼠前内的面 sutures
Hande Gorucu-Coskuner1,2, Mustafa Al-Yassary2, Kelly Billiaert2
1Department of Orthodontics, Hacettepe University, Ankara, Türkiye.
Frontiers in physiology
|July 3, 2023
概括
大鼠的面生长显示,从4周到16周,横向尺寸显著增加. 线宽度的变化不同,内线缩小,外线呈现多种变化,影响内发育.
科学领域:
- 头骨面部的发展
- 结构生物学 结构生物学
- 比较解剖学的比较解剖学
背景情况:
- 面 sutures 对于头骨的生长和发育至关重要.
- 了解形维度变化是理解整体面形态的关键.
研究的目的:
- 为了研究从4周到38周大老鼠的内鼻和鼻和相关的面尺寸的维度变化.
- 为了将头骨面部生长与部发育相关联.
主要方法:
- 微计算机断层扫描 (micro-CT) 用于扫描四个年龄组 (4,16,26,38周) 的Wistar大鼠.
- 测量包括横向的面尺寸 (鼻骨宽度,鼻间接的宽度,阴茎间接的宽度) 和接参数 (内,外和平均宽度;接高度).
- 相关系数评估了面和痕变化之间的关系.
主要成果:
- 横向的面尺寸从4周到16周显著增加.
- 在4至16周之间,脑内膜的宽度显著减少,青春期后没有显著的变化.
- 外和平均接宽度表现出复杂的变化,持续到成年早期,并且与横向面尺寸负相关.
结论:
- 在青少年时代,鼻间和鼻内内的宽度在很大程度上会稳定.
- 外和平均接宽度的变化持续到成年早期,影响内大脑的尺寸.
- 研究结果为研究对部发育和面生长的功能影响提供了参考.
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