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肺癌患者的开放性叶切除术后手术部位感染:一项前性研究
Shiyu Li1,2, Ji Lin2, Lijuan Ye3
1Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, P.R. China.
Journal of evidence-based medicine
|July 3, 2023
概括
手术部位感染 (SSIs) 在开放性肺叶切除术后很常见,影响患者的结果并增加成本. 识别诸如年龄和呼吸衰竭等危险因素对于预防至关重要.
科学领域:
- 胸部外科手术 胸部外科手术
- 传染病流行病学 传染病流行病学
- 医疗保健经济学 医疗保健经济学
背景情况:
- 手术部位感染 (SSI) 是胸部手术后的一个严重并发症.
- 开放性肺叶切除术带有术后感染的风险,并具有重大的临床和经济后果.
研究的目的:
- 为了确定SSI的发病率和确定SSI在开放性肺叶切除术后的风险因素.
- 在这个患者群体中量化与SSI相关的临床和经济负担.
主要方法:
- 一项前性嵌套病例控制研究,涉及1395名为肺癌接受开放性叶片切除术的患者.
- 数据收集包括人口统计,临床因素和医疗费用.
- 后勤回归和曼·惠特尼U测试用于风险因素分析和成本比较.
主要成果:
- 整体SSI发生率为13.47%,器官/空间感染是最常见的类型.
- 患有SSI的患者的死亡率明显增加,医疗费用增加,住院时间更长.
- 对SSI的独立风险因素包括晚年,呼吸衰竭,美国麻醉学会得分更高,操作时间更长,以及特定的操作团队.
结论:
- 开放性叶片切除术后SSI的高发病率强调了显著的临床负担.
- 未来的监测和及时识别风险因素可以帮助预防SSI并改善患者管理.
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